For any general questions and comments about the peer-review process, the journal or its editorial policies that are not addressed here, we encourage reviewers to contact us using the “contact us form” available at the right end of the website.

Image Integrity and Standards

Digital images submitted with a manuscript for review should be minimally processed. A certain degree of image processing is acceptable for publication (and for some experiments, fields and techniques is unavoidable), but the final image must correctly represent the original data and conform to community standards. Editors may use software to screen images for manipulation.

Editors may request the unprocessed data files to help in manuscript evaluation during the peer review process; if these data are unavailable upon request, we may need to halt the peer review process until the issues are satisfactorily resolved. We may also request unprocessed data when responding to post-publication issues that may arise with published papers. Lack of availability of unprocessed data can make resolution of post-publication issues challenging. We recommend retaining unprocessed data and metadata files after publication, ideally archiving data in perpetuity.